The Southern Swamp is home to the Deku Scrubs and is ruled by a fierce Deku King who resides in the Deku Palace. When Link first enters Southern Swamp, the water is poisoned due to the curse of the Woodfall Temple.

There is a second entrance leading into the Swamp that is accessible through a river in Ikana Canyon.

On top of the Swamp Tourist Center is a Piece of Heart, which can be accessed by presenting the Business Scrub with the Town Title Deed and using the Deku Flower to reach the roof.